England gave a debut to Yorkshire middle-order batsman Jonathan Bairstow, already capped at one-day international level, making him the 13th son to follow his father into the England Test team.
Bairstow's late father David, also a wicket-keeper/batsman, won four caps from 1979 to 1981. But the younger Bairstow was playing at Lord's as a number six batsman only, with Sussex gloveman Matt Prior continuing behind the stumps.
England left out seamers Steven Finn and Graham Onions from their 13-man squad, with pace bowling all-rounder Tim Bresnan -- victorious in all his 11 previous Tests -- joining quicks James Anderson and Stuart Broad in a four-man attack also featuring off-spinner Graeme Swann.
West Indies gave a Test debut to 24-year-old Trinidad paceman Shannon Gabriel after fast bowler Ravi Rampaul was ruled out with a stiff neck.
World number one-ranked Test side England were looking to re-establish their dominance after losing four out of five Tests against Pakistan and Sri Lanka on their winter tour.
West Indies came into the match having won just two out of their last 30 Tests